Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pik3r1  phosphoinositide-3-kinase regulatory subunit 1   (Synonyms: p50alpha, p55alpha, p85alpha, PI3K)
Results	Reference
1*	J:196196 Awuah PK, Nejak-Bowen KN, Monga SP, Role and Regulation of PDGFRalpha Signaling in Liver Development and Regeneration. Am J Pathol. 2013 May;182(5):1648-58
1	J:334838 Chang JH, Chou CH, Wu JC, Liao KM, Luo WJ, Hsu WL, Chen XR, Yu SL, Pan SH, Yang PC, Su KY, LCRMP-1 is required for spermatogenesis and stabilises spermatid F-actin organization via the PI3K-Akt pathway. Commun Biol. 2023 Apr 10;6(1):389
1	J:129381 Eickholt BJ, Ahmed AI, Davies M, Papakonstanti EA, Pearce W, Starkey ML, Bilancio A, Need AC, Smith AJ, Hall SM, Hamers FP, Giese KP, Bradbury EJ, Vanhaesebroeck B, Control of Axonal Growth and Regeneration of Sensory Neurons by the p110delta PI 3-Kinase. PLoS One. 2007;2(9):e869
1	J:109024 Foukas LC, Claret M, Pearce W, Okkenhaug K, Meek S, Peskett E, Sancho S, Smith AJ, Withers DJ, Vanhaesebroeck B, Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation. Nature. 2006 May 18;441(7091):366-70
1*	J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26
1	J:317070 Luo L, Jiang W, Liu H, Bu J, Tang P, Du C, Xu Z, Luo H, Liu B, Xiao B, Zhou Z, Liu F, De-silencing Grb10 contributes to acute ER stress-induced steatosis in mouse liver. J Mol Endocrinol. 2018 May;60(4):285-297
1	J:152699 Mouta-Bellum C, Kirov A, Miceli-Libby L, Mancini ML, Petrova TV, Liaw L, Prudovsky I, Thorpe PE, Miura N, Cantley LC, Alitalo K, Fruman DA, Vary CP, Organ-specific lymphangiectasia, arrested lymphatic sprouting, and maturation defects resulting from gene-targeting of the PI3K regulatory isoforms p85alpha, p55alpha, and p50alpha. Dev Dyn. 2009 Aug 24;238(10):2670-2679
1	J:233610 Peng Y, Lu Z, Li G, Piechowicz M, Anderson M, Uddin Y, Wu J, Qiu S, The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain. Mol Psychiatry. 2016 Jul;21(7):925-35
1	J:77800 Pimentel B, Rodriguez-Borlado L, Hernandez C, Carrera AC, A Role for phosphoinositide 3-kinase in the control of cell division and survival during retinal development. Dev Biol. 2002 Jul 15;247(2):295-306
1	J:311917 Qiu X, Wei R, Li Y, Zhu Q, Xiong C, Chen Y, Zhang Y, Lu K, He F, Zhang L, NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner. Oncotarget. 2016 May 24;7(21):31440-53
1	J:164696 Tan Y, You H, Coffey FJ, Wiest DL, Testa JR, Appl1 is dispensable for Akt signaling in vivo and mouse T-cell development. Genesis. 2010 Sep;48(9):531-9
1	J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54
1	J:239252 Zhang T, Yao Y, Wang J, Li Y, He P, Pasupuleti V, Hu Z, Jia X, Song Q, Tian XL, Hu C, Chen Q, Wang QK, Haploinsufficiency of Klippel-Trenaunay syndrome gene Aggf1 inhibits developmental and pathological angiogenesis by inactivating PI3K and AKT and disrupts vascular integrity by activating VE-cadherin. Hum Mol Genet. 2016 Dec 1;25(23):5094-5110
1	J:300786 Zhang Z, Ye M, Li Q, You Y, Yu H, Ma Y, Mei L, Sun X, Wang L, Yue W, Li R, Li J, Zhang D, The Schizophrenia Susceptibility Gene OPCML Regulates Spine Maturation and Cognitive Behaviors through Eph-Cofilin Signaling. Cell Rep. 2019 Oct 1;29(1):49-61.e7